Subclass and avidity of circumsporozoite protein specific antibodies associate with protection status against malaria infection

Subclass and avidity of circumsporozoite protein specific antibodies associate with protection status against malaria infection

Abstract RTS,S/AS01 is an advanced pre-erythrocytic malaria vaccine candidate with demonstrated vaccine efficacy up to 86.7% in controlled human malaria infection (CHMI) studies; however, reproducible immune correlates of protection (CoP) are elusive. To identify candidates of humoral correlates of...

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Détails bibliographiques
Auteurs principaux: Kelly E. Seaton, Rachel L. Spreng, Milite Abraha, Matthew Reichartz, Michelle Rojas, Frederick Feely, Richard H. C. Huntwork, Sheetij Dutta, Sarah V. Mudrak, S. Munir Alam, Scott Gregory, Erik Jongert, Margherita Coccia, Fernando Ulloa-Montoya, Ulrike Wille-Reece, Georgia D. Tomaras, S. Moses Dennison
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Immunologic diseases. Allergy
RC581-607
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Accès en ligne:https://doaj.org/article/0219a60f06354a4495a0f6088c161287
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Internet

https://doaj.org/article/0219a60f06354a4495a0f6088c161287

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