Berberine Derivatives as <i>Pseudomonas aeruginosa</i> MexXY-OprM Inhibitors: Activity and In Silico Insights
The natural alkaloid berberine has been demonstrated to inhibit the <i>Pseudomonas aeruginosa</i> multidrug efflux system MexXY-OprM, which is responsible for tobramycin extrusion by binding the inner membrane transporter MexY. To find a structure with improved inhibitory activity, we co...
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| Autores principales: | , , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
MDPI AG
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/0260bdc7601d46bcb7d1ad71a4ced2cb |
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