Understanding the connection between epigenetic DNA methylation and nucleosome positioning from computer simulations.
Cytosine methylation is one of the most important epigenetic marks that regulate the process of gene expression. Here, we have examined the effect of epigenetic DNA methylation on nucleosomal stability using molecular dynamics simulations and elastic deformation models. We found that methylation of...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2013
|
| Subjects: | |
| Online Access: | https://doaj.org/article/029f6b54fbd841eaafacdc02fb87eabd |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!