Formalin-inactivated EV71 vaccine candidate induced cross-neutralizing antibody against subgenotypes B1, B4, B5 and C4A in adult volunteers.

Formalin-inactivated EV71 vaccine candidate induced cross-neutralizing antibody against subgenotypes B1, B4, B5 and C4A in adult volunteers.

<h4>Background</h4>Enterovirus 71 (EV71) has caused several epidemics of hand, foot and mouth diseases (HFMD) in Asia. No effective EV71 vaccine is available. A randomized and open-label phase I clinical study registered with ClinicalTrials.gov #NCT01268787, aims to evaluate the safety,...

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Main Authors: Ai-Hsiang Chou, Chia-Chyi Liu, Jui-Yuan Chang, Renee Jiang, Yi-Chin Hsieh, Amanda Tsao, Chien-Long Wu, Ju-Lan Huang, Chang-Phone Fung, Szu-Min Hsieh, Ya-Fang Wang, Jen-Ren Wang, Mei-Hua Hu, Jen-Ron Chiang, Ih-Jen Su, Pele Choi-Sing Chong
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/029ff0ba187d4cfbb57b9ff9cc475b54
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https://doaj.org/article/029ff0ba187d4cfbb57b9ff9cc475b54

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