Electron cryo-tomography reveals the subcellular architecture of growing axons in human brain organoids

During brain development, axons must extend over great distances in a relatively short amount of time. How the subcellular architecture of the growing axon sustains the requirements for such rapid build-up of cellular constituents has remained elusive. Human axons have been particularly poorly acces...

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Bibliographic Details
Main Authors: Patrick C Hoffmann, Stefano L Giandomenico, Iva Ganeva, Michael R Wozny, Magdalena Sutcliffe, Madeline A Lancaster, Wanda Kukulski
Format: article
Language:EN
Published: eLife Sciences Publications Ltd 2021
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Online Access:https://doaj.org/article/02bc299a719544eaa41e48038e4ecda2
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