The dimer-monomer equilibrium of SARS-CoV-2 main protease is affected by small molecule inhibitors

The dimer-monomer equilibrium of SARS-CoV-2 main protease is affected by small molecule inhibitors

Abstract The maturation of coronavirus SARS-CoV-2, which is the etiological agent at the origin of the COVID-19 pandemic, requires a main protease Mpro to cleave the virus-encoded polyproteins. Despite a wealth of experimental information already available, there is wide disagreement about the Mpro...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Lucia Silvestrini, Norhan Belhaj, Lucia Comez, Yuri Gerelli, Antonino Lauria, Valeria Libera, Paolo Mariani, Paola Marzullo, Maria Grazia Ortore, Antonio Palumbo Piccionello, Caterina Petrillo, Lucrezia Savini, Alessandro Paciaroni, Francesco Spinozzi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/02bfcfccb4f9426583834a691e65e91b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/02bfcfccb4f9426583834a691e65e91b

Ejemplares similares