Polyamines Upregulate Cephalosporin C Production and Expression of β-Lactam Biosynthetic Genes in High-Yielding <i>Acremonium chrysogenum</i> Strain

The high-yielding production of pharmaceutically significant secondary metabolites in filamentous fungi is obtained by random mutagenesis; such changes may be associated with shifts in the metabolism of polyamines. We have previously shown that, in the <i>Acremonium chrysogenum</i> cepha...

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Autores principales: Alexander A. Zhgun, Mikhail A. Eldarov
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/02c53477827742fe8593a9c78549d77c
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