Detection of 2-Hydroxyglutarate by 3.0-Tesla Magnetic Resonance Spectroscopy in Gliomas with Rare IDH Mutations: Making Sense of “False-Positive” Cases

Detection of 2-Hydroxyglutarate by 3.0-Tesla Magnetic Resonance Spectroscopy in Gliomas with Rare IDH Mutations: Making Sense of “False-Positive” Cases

We have previously published a study on the reliable detection of 2-hydroxyglutarate (2HG) in lower-grade gliomas by magnetic resonance spectroscopy (MRS). In this short article, we re-evaluated five glioma cases originally assessed as isocitrate dehydrogenase (IDH) wildtype, which showed a high acc...

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Autores principales: Manabu Natsumeda, Hironaka Igarashi, Ramil Gabdulkhaev, Haruhiko Takahashi, Kunio Motohashi, Ryosuke Ogura, Jun Watanabe, Yoshihiro Tsukamoto, Kouichirou Okamoto, Akiyoshi Kakita, Tsutomu Nakada, Yukihiko Fujii
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
2-hydroxyglutarate
glioma
magnetic resonance spectroscopy
rare IDH mutations
false-positive
Medicine (General)
R5-920
Acceso en línea:https://doaj.org/article/02c8ce6392cb47eda48b441c0572e5df
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https://doaj.org/article/02c8ce6392cb47eda48b441c0572e5df

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