Nanostructures of diamond, graphene oxide and graphite inhibit CYP1A2, CYP2D6 and CYP3A4 enzymes and downregulate their genes in liver cells

Nanostructures of diamond, graphene oxide and graphite inhibit CYP1A2, CYP2D6 and CYP3A4 enzymes and downregulate their genes in liver cells

Barbara Strojny,1 Ewa Sawosz,1 Marta Grodzik,1 Sławomir Jaworski,1 Jarosław Szczepaniak,1 Malwina Sosnowska,1 Mateusz Wierzbicki,1 Marta Kutwin,1 Sylwia Orlińska,1 André Chwalibog2 1Division of Nanobiotechnology, Warsaw University of Life Sciences, Warsaw, Poland; 2Department of Veterina...

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Autores principales: Strojny B, Sawosz E, Grodzik M, Jaworski S, Szczepaniak J, Sosnowska M, Wierzbicki M, Kutwin M, Orlińska S, Chwalibog A
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2018
Materias:
carbon nanostructures
nanoparticles
cytochrome P450
microsomes
liver
Medicine (General)
R5-920
Acceso en línea:https://doaj.org/article/02e1b06a0e0e452ca4cd05ae4dd9daaf
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https://doaj.org/article/02e1b06a0e0e452ca4cd05ae4dd9daaf

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