Structural basis of the molecular ruler mechanism of a bacterial glycosyltransferase

The glycosyltransferase PglH transfers three terminal N-acetylgalactosamine (GalNAc) residues to a carrier, which is a prerequisite for bacterial protein N-glycosylation. Here authors present the crystal structures of PglH in three distinct states and show that a ‘ruler helix’ facilitates membrane a...

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Bibliographic Details
Main Authors: Ana S. Ramírez, Jérémy Boilevin, Ahmad Reza Mehdipour, Gerhard Hummer, Tamis Darbre, Jean-Louis Reymond, Kaspar P. Locher
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/02fd06bf76d44363ac10479a0e87396b
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