A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links

When DNA interstrand cross-links damage occurs, it causes disruption of replication and transcription. Here the authors identify FAM120B/SAN1, a 5′ exonuclease involved in the repair process of Interstrand Crosslinks independently of the Fanconi Anemia pathway.

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Autores principales:	Alex M. Andrews, Heather J. McCartney, Tim M. Errington, Alan D. D’Andrea, Ian G. Macara
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/031ac7b17c8c4e12a4254e48a3e6d6a6
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spelling	oai:doaj.org-article:031ac7b17c8c4e12a4254e48a3e6d6a62021-12-02T15:34:43ZA senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links10.1038/s41467-018-05008-82041-1723https://doaj.org/article/031ac7b17c8c4e12a4254e48a3e6d6a62018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05008-8https://doaj.org/toc/2041-1723When DNA interstrand cross-links damage occurs, it causes disruption of replication and transcription. Here the authors identify FAM120B/SAN1, a 5′ exonuclease involved in the repair process of Interstrand Crosslinks independently of the Fanconi Anemia pathway.Alex M. AndrewsHeather J. McCartneyTim M. ErringtonAlan D. D’AndreaIan G. MacaraNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alex M. Andrews Heather J. McCartney Tim M. Errington Alan D. D’Andrea Ian G. Macara A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links
description	When DNA interstrand cross-links damage occurs, it causes disruption of replication and transcription. Here the authors identify FAM120B/SAN1, a 5′ exonuclease involved in the repair process of Interstrand Crosslinks independently of the Fanconi Anemia pathway.
format	article
author	Alex M. Andrews Heather J. McCartney Tim M. Errington Alan D. D’Andrea Ian G. Macara
author_facet	Alex M. Andrews Heather J. McCartney Tim M. Errington Alan D. D’Andrea Ian G. Macara
author_sort	Alex M. Andrews
title	A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links
title_short	A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links
title_full	A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links
title_fullStr	A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links
title_full_unstemmed	A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links
title_sort	senataxin-associated exonuclease san1 is required for resistance to dna interstrand cross-links
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/031ac7b17c8c4e12a4254e48a3e6d6a6
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A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links

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