Evidence that the TRPV1 S1-S4 membrane domain contributes to thermosensing
The TRPV1 ion channel is a heat-sensing receptor that is also activated by vanilloid compounds, but the molecular underpinnings of thermosensing have remained elusive. Here authors use in solution NMR on the isolated human TRPV1 S1-S4 domain and show that this domain undergoes a non-denaturing tempe...
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Auteurs principaux: | , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2020
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Accès en ligne: | https://doaj.org/article/031b403abc3941b8bfde584589cc3cd7 |
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