Crystal structures of non-oxidative decarboxylases reveal a new mechanism of action with a catalytic dyad and structural twists

Abstract Hydroxybenzoic acids, like gallic acid and protocatechuic acid, are highly abundant natural compounds. In biotechnology, they serve as critical precursors for various molecules in heterologous production pathways, but a major bottleneck is these acids’ non-oxidative decarboxylation to hydro...

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Autores principales: Matthias Zeug, Nebojsa Markovic, Cristina V. Iancu, Joanna Tripp, Mislav Oreb, Jun-yong Choe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/032368842d7f4b36972b7a1662d3f5a3
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