Caffeine inhibits hypothalamic A1R to excite oxytocin neuron and ameliorate dietary obesity in mice

The mechanism by which caffeine, an antagonist of adenosine receptors, regulates metabolism is not clear. Here the authors show that adenosine A1R receptor expression is increased in the hypothalamus of diet-induced obesity mice, and that body weight can be alleviated by central administration of ca...

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Bibliographic Details
Main Authors: Liufeng Wu, Jia Meng, Qing Shen, Yi Zhang, Susu Pan, Zhuo Chen, Ling-Qiang Zhu, Youming Lu, Yuan Huang, Guo Zhang
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/0330342e5f7e48ee99ed295bb8642fea
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