Caffeine inhibits hypothalamic A1R to excite oxytocin neuron and ameliorate dietary obesity in mice

The mechanism by which caffeine, an antagonist of adenosine receptors, regulates metabolism is not clear. Here the authors show that adenosine A1R receptor expression is increased in the hypothalamus of diet-induced obesity mice, and that body weight can be alleviated by central administration of ca...

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Autores principales: Liufeng Wu, Jia Meng, Qing Shen, Yi Zhang, Susu Pan, Zhuo Chen, Ling-Qiang Zhu, Youming Lu, Yuan Huang, Guo Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/0330342e5f7e48ee99ed295bb8642fea
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