YfiBNR mediates cyclic di-GMP dependent small colony variant formation and persistence in Pseudomonas aeruginosa.
During long-term cystic fibrosis lung infections, Pseudomonas aeruginosa undergoes genetic adaptation resulting in progressively increased persistence and the generation of adaptive colony morphotypes. This includes small colony variants (SCVs), auto-aggregative, hyper-adherent cells whose appearanc...
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Main Authors: | Jacob G Malone, Tina Jaeger, Christian Spangler, Daniel Ritz, Anne Spang, Cécile Arrieumerlou, Volkhard Kaever, Regine Landmann, Urs Jenal |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2010
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Online Access: | https://doaj.org/article/033ff0e881fc4552bf4c7a65e6fb6db8 |
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