Focused peptide library screening as a route to a superior affinity ligand for antibody purification

Abstract Affinity chromatography is the linchpin of antibody downstream processing and typically relies on bacterial immunoglobulin (Ig)-binding proteins, epitomized by staphylococcal protein A-based ligands. However, such affinity ligands are fairly costly and suffer from chemical instability, lead...

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Bibliographic Details
Main Authors: Krištof Bozovičar, Barbara Jenko Bizjan, Anže Meden, Jernej Kovač, Tomaž Bratkovič
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/034316d8ed774a0db32666981738785c
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