Epidemiological hypothesis testing using a phylogeographic and phylodynamic framework

Classical epidemiological approaches have been limited in their ability to formally test hypotheses. Here, Dellicour et al. illustrate how phylodynamic and phylogeographic analyses can be leveraged for hypothesis testing in molecular epidemiology using West Nile virus in North America as an example.

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Autores principales: Simon Dellicour, Sebastian Lequime, Bram Vrancken, Mandev S. Gill, Paul Bastide, Karthik Gangavarapu, Nathaniel L. Matteson, Yi Tan, Louis du Plessis, Alexander A. Fisher, Martha I. Nelson, Marius Gilbert, Marc A. Suchard, Kristian G. Andersen, Nathan D. Grubaugh, Oliver G. Pybus, Philippe Lemey
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/034b011214474575a5f47f436fad92f5
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spelling oai:doaj.org-article:034b011214474575a5f47f436fad92f52021-12-02T14:40:50ZEpidemiological hypothesis testing using a phylogeographic and phylodynamic framework10.1038/s41467-020-19122-z2041-1723https://doaj.org/article/034b011214474575a5f47f436fad92f52020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19122-zhttps://doaj.org/toc/2041-1723Classical epidemiological approaches have been limited in their ability to formally test hypotheses. Here, Dellicour et al. illustrate how phylodynamic and phylogeographic analyses can be leveraged for hypothesis testing in molecular epidemiology using West Nile virus in North America as an example.Simon DellicourSebastian LequimeBram VranckenMandev S. GillPaul BastideKarthik GangavarapuNathaniel L. MattesonYi TanLouis du PlessisAlexander A. FisherMartha I. NelsonMarius GilbertMarc A. SuchardKristian G. AndersenNathan D. GrubaughOliver G. PybusPhilippe LemeyNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Simon Dellicour
Sebastian Lequime
Bram Vrancken
Mandev S. Gill
Paul Bastide
Karthik Gangavarapu
Nathaniel L. Matteson
Yi Tan
Louis du Plessis
Alexander A. Fisher
Martha I. Nelson
Marius Gilbert
Marc A. Suchard
Kristian G. Andersen
Nathan D. Grubaugh
Oliver G. Pybus
Philippe Lemey
Epidemiological hypothesis testing using a phylogeographic and phylodynamic framework
description Classical epidemiological approaches have been limited in their ability to formally test hypotheses. Here, Dellicour et al. illustrate how phylodynamic and phylogeographic analyses can be leveraged for hypothesis testing in molecular epidemiology using West Nile virus in North America as an example.
format article
author Simon Dellicour
Sebastian Lequime
Bram Vrancken
Mandev S. Gill
Paul Bastide
Karthik Gangavarapu
Nathaniel L. Matteson
Yi Tan
Louis du Plessis
Alexander A. Fisher
Martha I. Nelson
Marius Gilbert
Marc A. Suchard
Kristian G. Andersen
Nathan D. Grubaugh
Oliver G. Pybus
Philippe Lemey
author_facet Simon Dellicour
Sebastian Lequime
Bram Vrancken
Mandev S. Gill
Paul Bastide
Karthik Gangavarapu
Nathaniel L. Matteson
Yi Tan
Louis du Plessis
Alexander A. Fisher
Martha I. Nelson
Marius Gilbert
Marc A. Suchard
Kristian G. Andersen
Nathan D. Grubaugh
Oliver G. Pybus
Philippe Lemey
author_sort Simon Dellicour
title Epidemiological hypothesis testing using a phylogeographic and phylodynamic framework
title_short Epidemiological hypothesis testing using a phylogeographic and phylodynamic framework
title_full Epidemiological hypothesis testing using a phylogeographic and phylodynamic framework
title_fullStr Epidemiological hypothesis testing using a phylogeographic and phylodynamic framework
title_full_unstemmed Epidemiological hypothesis testing using a phylogeographic and phylodynamic framework
title_sort epidemiological hypothesis testing using a phylogeographic and phylodynamic framework
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/034b011214474575a5f47f436fad92f5
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