Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function

Aging is associated with a progressive loss of muscle function. Here the authors characterize mitochondrial capacity and muscle function in young and older adults with similar habitual physical activity and also compared to older adults with exercise training or with physical impairment.

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Bibliographic Details
Main Authors: L. Grevendonk, N. J. Connell, C. McCrum, C. E. Fealy, L. Bilet, Y. M. H. Bruls, J. Mevenkamp, V. B. Schrauwen-Hinderling, J. A. Jörgensen, E. Moonen-Kornips, G. Schaart, B. Havekes, J. de Vogel-van den Bosch, M. C. E. Bragt, K. Meijer, P. Schrauwen, J. Hoeks
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/035190f53f0041ab9013b063d3712f34
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Summary:Aging is associated with a progressive loss of muscle function. Here the authors characterize mitochondrial capacity and muscle function in young and older adults with similar habitual physical activity and also compared to older adults with exercise training or with physical impairment.