Supramolecular trap for catching polyamines in cells as an anti-tumor strategy

Polyamines are essential for cell growth and are frequently increased in concentration in cancer cells. Here, the authors use a macrocycle to generate a supramolecular trap, which depletes the polyamines in cells, induces apoptosis and reduces cancer cell growth in mice.

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Detalles Bibliográficos
Autores principales: Junyi Chen, Hanzhi Ni, Zhao Meng, Jing Wang, Xiayang Huang, Yansheng Dong, Chao Sun, Yadan Zhang, Lei Cui, Jian Li, Xueshun Jia, Qingbin Meng, Chunju Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/036605c0fa524d228d5ca0375dc359af
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