Thyroid hormones derivatives reduce proliferation and induce cell death and DNA damage in ovarian cancer

Abstract Ovarian cancer is a highly aggressive disease and novel treatments are required. Thyroid hormones binding to αvβ3 integrin produced growth-promoting activities in ovarian cancer and we hypothesized that natural thyroid hormone derivatives may antagonize these actions. The effect of three an...

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Autores principales: Elena Shinderman-Maman, Keren Cohen, Dotan Moskovich, Aleck Hercbergs, Haim Werner, Paul J. Davis, Martin Ellis, Osnat Ashur-Fabian
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/0387e756b4e9437087dee0edd92fdf52
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