Completion of hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines.

Completion of hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines.

Hepatitis C virus (HCV) is hepatotropic and only infects humans and chimpanzees. Consequently, an immunocompetent small animal model is lacking. The restricted tropism of HCV likely reflects specific host factor requirements. We investigated if dominant restriction factors expressed in non-liver or...

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Bibliographic Details
Main Authors: Anne Frentzen, Kathrin Hüging, Julia Bitzegeio, Martina Friesland, Sibylle Haid, Juliane Gentzsch, Markus Hoffmann, Dirk Lindemann, Gert Zimmer, Florian Zielecki, Friedemann Weber, Eike Steinmann, Thomas Pietschmann
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/03bb75b6def04b5299f335b771c7e8d4
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https://doaj.org/article/03bb75b6def04b5299f335b771c7e8d4

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