A combinatorial approach to detect coevolved amino acid networks in protein families of variable divergence.

Communication between distant sites often defines the biological role of a protein: amino acid long-range interactions are as important in binding specificity, allosteric regulation and conformational change as residues directly contacting the substrate. The maintaining of functional and structural...

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Autores principales: Julie Baussand, Alessandra Carbone
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/03c328528ed146d98a4e592788d959a5
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