Organocatalytic atroposelective construction of axially chiral arylquinones

Axially chiral compounds have widespread use in asymmetric catalysis. Here, the authors disclose a highly enantioselective synthesis of axially chiral o-naphthoquinones by chiral phosphoric acid catalysis and central-to-axial chirality conversion.

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Bibliographic Details
Main Authors: Shuai Zhu, Ye-Hui Chen, Yong-Bin Wang, Peiyuan Yu, Shao-Yu Li, Shao-Hua Xiang, Jun-Qi Wang, Jian Xiao, Bin Tan
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Q
Online Access:https://doaj.org/article/03c6732f031d4be7b207e6e3dc60046e
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