CRISPR Interference of a Clonally Variant GC-Rich Noncoding RNA Family Leads to General Repression of <italic toggle="yes">var</italic> Genes in <named-content content-type="genus-species">Plasmodium falciparum</named-content>
ABSTRACT The human malaria parasite Plasmodium falciparum uses mutually exclusive expression of the PfEMP1-encoding var gene family to evade the host immune system. Despite progress in the molecular understanding of the default silencing mechanism, the activation mechanism of the uniquely expressed...
Guardado en:
Autores principales: | , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/03d722d0147f412f860ff784e5a0530e |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|