Citalopram inhibits platelet function independently of SERT-mediated 5-HT transport

Abstract Citalopram prevents serotonin (5-HT) uptake into platelets by blocking the serotonin reuptake transporter (SERT). Although some clinical data suggest that selective serotonin reuptake inhibitors (SSRIs) may affect haemostasis and thrombosis, these poorly-characterised effects are not well u...

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Autores principales: Harvey G. Roweth, Ruoling Yan, Nader H. Bedwani, Alisha Chauhan, Nicole Fowler, Alice H. Watson, Jean-Daniel Malcor, Stewart O. Sage, Gavin E. Jarvis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/03e1a156b5144db0b5daf6945d11679e
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