Identification of a membrane-less compartment regulating invadosome function and motility

Abstract Depletion of liprin-α1, ERC1 or LL5 scaffolds inhibits extracellular matrix degradation by invasive cells. These proteins co-accumulate near invadosomes in NIH-Src cells, identifying a novel invadosome–associated compartment distinct from the core and adhesion ring of invadosomes. Depletion...

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Autores principales: Kristyna Sala, Andrea Raimondi, Diletta Tonoli, Carlo Tacchetti, Ivan de Curtis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/03f68b9343d147fab5c3d0fb2c1ff904
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