Identification of a membrane-less compartment regulating invadosome function and motility
Abstract Depletion of liprin-α1, ERC1 or LL5 scaffolds inhibits extracellular matrix degradation by invasive cells. These proteins co-accumulate near invadosomes in NIH-Src cells, identifying a novel invadosome–associated compartment distinct from the core and adhesion ring of invadosomes. Depletion...
Enregistré dans:
Auteurs principaux: | Kristyna Sala, Andrea Raimondi, Diletta Tonoli, Carlo Tacchetti, Ivan de Curtis |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/03f68b9343d147fab5c3d0fb2c1ff904 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Client proximity enhancement inside cellular membrane-less compartments governed by client-compartment interactions
par: Daesun Song, et autres
Publié: (2020) -
Physical observables to determine the nature of membrane-less cellular sub-compartments
par: Mathias L Heltberg, et autres
Publié: (2021) -
Rac1 and Rac3 GTPases regulate the development of hilar mossy cells by affecting the migration of their precursors to the hilus.
par: Roberta Pennucci, et autres
Publié: (2011) -
The Large GTPase, GBP-2, Regulates Rho Family GTPases to Inhibit Migration and Invadosome Formation in Breast Cancer Cells
par: Geoffrey O. Nyabuto, et autres
Publié: (2021) -
Combining laser capture microdissection and proteomics reveals an active translation machinery controlling invadosome formation
par: Zakaria Ezzoukhry, et autres
Publié: (2018)