Positive symptom phenotypes appear progressively in “EDiPS”, a new animal model of the schizophrenia prodrome

Abstract An increase in dopamine (DA) synthesis capacity in the dorsal striatum (DS) during the prodromal stage of schizophrenia becomes more pronounced as patients progress to the full disorder. Understanding this progression is critical to intervening in disease course. We developed an animal mode...

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Autores principales: Alice Petty, Xiaoying Cui, Asad Ali, Zilong Du, Sunil Srivastav, James P. Kesby, Deniz Kirik, Oliver Howes, Darryl Eyles
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/041501d82fe64bce8596a7893fcb044b
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