The evolution and appearance of C3 duplications in fish originate an exclusive teleost c3 gene form with anti-inflammatory activity.

The complement system acts as a first line of defense and promotes organism homeostasis by modulating the fates of diverse physiological processes. Multiple copies of component genes have been previously identified in fish, suggesting a key role for this system in aquatic organisms. Herein, we confi...

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Auteurs principaux: Gabriel Forn-Cuní, Edimara S Reis, Sonia Dios, David Posada, John D Lambris, Antonio Figueras, Beatriz Novoa
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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R
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Accès en ligne:https://doaj.org/article/041819efb5a94058bb2e5573d53cc5b2
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