A role for annexin A2 in scaffolding the peroxiredoxin 2–STAT3 redox relay complex

Peroxiredoxin 2 (Prx2) was previously shown to transfer H2O2-derived oxidative equivalents to STAT3, generating disulfide-linked dimers and tetramers. Here the authors show that the interaction between Prx2 and STAT3 at the plasma membrane is mediated by the membrane chaperone annexin A2; suggesting...

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Autores principales: Deepti Talwar, Joris Messens, Tobias P. Dick
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/0437c00ea49c4b13ae922c900e305b00
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