Aristolochic Acid Induces Renal Fibrosis and Senescence in Mice

Aristolochic Acid Induces Renal Fibrosis and Senescence in Mice

The kidney is one of the most susceptible organs to age-related impairments. Generally, renal aging is accompanied by renal fibrosis, which is the final common pathway of chronic kidney diseases. Aristolochic acid (AA), a nephrotoxic agent, causes AA nephropathy (AAN), which is characterized by prog...

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Autores principales: Shingo Urate, Hiromichi Wakui, Kengo Azushima, Takahiro Yamaji, Toru Suzuki, Eriko Abe, Shohei Tanaka, Shinya Taguchi, Shunichiro Tsukamoto, Sho Kinguchi, Kazushi Uneda, Tomohiko Kanaoka, Yoshitoshi Atobe, Kengo Funakoshi, Akio Yamashita, Kouichi Tamura
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
chronic kidney disease
renal fibrosis
aristolochic acid
aging
cellular senescence
Biology (General)
QH301-705.5
Chemistry
QD1-999
Acceso en línea:https://doaj.org/article/045f894d93e7448a9509537adb128ec4
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https://doaj.org/article/045f894d93e7448a9509537adb128ec4

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