Evaluating dopamine transporter imaging as an enrichment biomarker in a phase 2 Parkinson’s disease trial

Abstract Background Dopamine transporter single-photon emission computed tomography (DaT-SPECT) can quantify the functional integrity of the dopaminergic nerve terminals and has been suggested as an imaging modality to verify the clinical diagnosis of Parkinson’s disease (PD). Depending on the stage...

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Autores principales: R. Matthew Hutchison, Karleyton C. Evans, Tara Fox, Minhua Yang, Jerome Barakos, Barry J. Bedell, Jesse M. Cedarbaum, Miroslaw Brys, Andrew Siderowf, Anthony E. Lang
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/0488346b56e840c7bd83cdfb6e977f97
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