Cdc6 contributes to abrogating the G1 checkpoint under hypoxic conditions in HPV E7 expressing cells

Abstract The human papillomavirus (HPV) plays a central role in cervical carcinogenesis and its oncogene E7 is essential in this process. We showed here that E7 abrogated the G1 cell cycle checkpoint under hypoxia and analyzed key cell cycle related proteins for their potential role in this process....

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Autores principales: Hanxiang Chen, Qishu Zhang, Lijun Qiao, Xueli Fan, Weifang Zhang, Weiming Zhao, Jason J. Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/04b85512866f468bb2551c1476b8588a
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