Stage-resolved Hi-C analyses reveal meiotic chromosome organizational features influencing homolog alignment

During meiosis, chromosomes undergo dramatic changes in morphology and intranuclear positioning. Here the authors mapped the 3D genome architecture throughout mouse spermatogenesis by Hi-C of sorted cells to reveal the contributions of transcriptional activity and mechanical force in modulating homo...

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Autores principales: Wu Zuo, Guangming Chen, Zhimei Gao, Shuai Li, Yanyan Chen, Chenhui Huang, Juan Chen, Zhengjun Chen, Ming Lei, Qian Bian
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/04bab0aa74074e349ddf98974f462098
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