Nanogels of dual inhibitor-modified hyaluronic acid function as a potent inhibitor of amyloid β-protein aggregation and cytotoxicity
Abstract Inhibition of amyloid β-protein (Aβ) aggregation is considered as a promising strategy for the prevention and treatment of Alzheimer’s disease. Epigallocatechin-3-gallate (EGCG) and curcumin have been recognized as effective inhibitors of Aβ aggregation. Herein, we proposed dual-inhibitor m...
Enregistré dans:
Auteurs principaux: | Zhiqiang Jiang, Xiaoyan Dong, Xin Yan, Yang Liu, Lin Zhang, Yan Sun |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/04fd691b19d24725a105db320c64861c |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function
par: L. Palanikumar, et autres
Publié: (2021) -
In Vitro Intestinal Uptake And Permeability Of Fluorescently-Labelled Hyaluronic Acid Nanogels
par: Xavier M, et autres
Publié: (2019) -
Cytotoxic aggregation and amyloid formation by the myostatin precursor protein.
par: Carlene S Starck, et autres
Publié: (2010) -
Effective screen for amyloid β aggregation inhibitor using amyloid β-conjugated gold nanoparticles
par: Sun-Ho Han, et autres
Publié: (2010) -
Computational design of new Peptide inhibitors for amyloid Beta (aβ) aggregation in Alzheimer's disease: application of a novel methodology.
par: Gözde Eskici, et autres
Publié: (2013)