Nanogels of dual inhibitor-modified hyaluronic acid function as a potent inhibitor of amyloid β-protein aggregation and cytotoxicity

Nanogels of dual inhibitor-modified hyaluronic acid function as a potent inhibitor of amyloid β-protein aggregation and cytotoxicity

Abstract Inhibition of amyloid β-protein (Aβ) aggregation is considered as a promising strategy for the prevention and treatment of Alzheimer’s disease. Epigallocatechin-3-gallate (EGCG) and curcumin have been recognized as effective inhibitors of Aβ aggregation. Herein, we proposed dual-inhibitor m...

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Bibliographic Details
Main Authors: Zhiqiang Jiang, Xiaoyan Dong, Xin Yan, Yang Liu, Lin Zhang, Yan Sun
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/04fd691b19d24725a105db320c64861c
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