Deep generative model embedding of single-cell RNA-Seq profiles on hyperspheres and hyperbolic spaces

Single-cell RNA-seq allows the study of tissues at cellular resolution. Here, the authors demonstrate how deep learning can be used to gain biological insight from such data by accounting for biological and technical variability. Data exploration is improved by accurately visualizing cells on an int...

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Auteurs principaux: Jiarui Ding, Aviv Regev
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/050105f7e38d42cba8c66492f371e672
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