Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells
Vito et al. investigated the effects of combination therapy in a TNBC tumor model and reported increased tumor-infiltrating lymphocytes that contributed to an improved response to immune checkpoint blockade. By depletion of circulating B cells prior to therapy, the authors showed a loss of therapeut...
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Main Authors: | , , , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/05222c9ff4534f789861496bd23f86ca |
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