EGFR and PDGFRA co-expression and heterodimerization in glioblastoma tumor sphere lines

Abstract Concurrent amplifications of EGFR and PDGFRA have been reported in up to 5% of glioblastoma (GBM) and it remains unclear why such independent amplification events, and associated receptor overexpression, would be adaptive during glioma evolution. Here, we document that EGFR and PDGFRA prote...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Debyani Chakravarty, Alicia M. Pedraza, Jesse Cotari, Angela H. Liu, Diana Punko, Aushim Kokroo, Jason T. Huse, Gregoire Altan-Bonnet, Cameron W. Brennan
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/052b404398294acfaa36d10454862c2e
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!