Robust homology-directed repair within mouse mammary tissue is not specifically affected by Brca2 mutation
Mutations in homology-directed repair genes likeBRCA2are linked to breast cancer susceptibility. Here the authors generate mice with an inducible DNA break-reporter system and see high levels of homology-directed repair in proliferative mammary tissue and a general reliance on BRCA2 in various tissu...
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| Autores principales: | , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2016
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/05628ecc62f8432486b6a2626164ba2c |
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