The role of protease-activated receptor 1 signaling in CD8 T cell effector functions

The role of protease-activated receptor 1 signaling in CD8 T cell effector functions

Summary: CD8 T cells are essential for adaptive immunity against viral infections. Protease activated receptor 1 (PAR1) is expressed by CD8 T cells; however, its role in T cell effector function is not well defined. Here we show that in human CD8 T cells, PAR1 stimulation accelerates calcium mobiliz...

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Bibliographic Details
Main Authors: Hui Chen, Mindy Smith, Jasmin Herz, Tong Li, Rebecca Hasley, Cecile Le Saout, Ziang Zhu, Jie Cheng, Andres Gronda, José A. Martina, Pablo M. Irusta, Tatiana Karpova, Dorian B. McGavern, Marta Catalfamo
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Molecular biology
Immunology
Immune response
Science
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Online Access:https://doaj.org/article/059bb0b455fd410090bd8cec3665286e
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https://doaj.org/article/059bb0b455fd410090bd8cec3665286e

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