Shift of EMT gradient in 3D spheroid MSCs for activation of mesenchymal niche function

Abstract Despite the wide use of mesenchymal stromal cells (MSCs) for paracrine support in clinical trials, their variable and heterogeneous supporting activity pose major challenges. While three-dimensional (3D) MSC cultures are emerging as alternative approaches, key changes in cellular characteri...

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Bibliographic Details
Main Authors: Sohee Jeon, Ho-Sun Lee, Ga-Young Lee, Gyeongsin Park, Tae-Min Kim, Jihye Shin, Cheolju Lee, Il-Hoan Oh
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
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Online Access:https://doaj.org/article/05c7820835e242239d012f3c5b2ec563
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