In vivo analysis of the Notch receptor S1 cleavage.

A ligand-independent cleavage (S1) in the extracellular domain of the mammalian Notch receptor results in what is considered to be the canonical heterodimeric form of Notch on the cell surface. The in vivo consequences and significance of this cleavage on Drosophila Notch signaling remain unclear an...

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Bibliographic Details
Main Authors: Robert J Lake, Lisa M Grimm, Alexey Veraksa, Andrew Banos, Spyros Artavanis-Tsakonas
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2009
Subjects:
R
Q
Online Access:https://doaj.org/article/05d2fdc75ee043be924eac48fa9137ac
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