Metabolite changes in blood predict the onset of tuberculosis
The tuberculosis pandemic requires new methods for diagnosing and containing infections prior to active disease. Here, the authors performed a multi-site observational study within sub-Saharan Africa and present serum and plasma metabolic signatures that can predict the onset of active TB with a hig...
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Nature Portfolio
2018
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oai:doaj.org-article:05ed44b4c9294316afa2b3d18f1beb1a2021-12-02T16:49:34ZMetabolite changes in blood predict the onset of tuberculosis10.1038/s41467-018-07635-72041-1723https://doaj.org/article/05ed44b4c9294316afa2b3d18f1beb1a2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07635-7https://doaj.org/toc/2041-1723The tuberculosis pandemic requires new methods for diagnosing and containing infections prior to active disease. Here, the authors performed a multi-site observational study within sub-Saharan Africa and present serum and plasma metabolic signatures that can predict the onset of active TB with a high degree of sensitivity and specificity.January WeinerJeroen MaertzdorfJayne S. SutherlandFergal J. DuffyEthan ThompsonSara SulimanGayle McEwenBonnie ThielShreemanta K. ParidaJoanna ZylaWillem A. HanekomRobert P. MohneyW. Henry BoomHarriet Mayanja-KizzaRawleigh HoweHazel M. DockrellTom H. M. OttenhoffThomas J. ScribaDaniel E. ZakGerhard WalzlStefan H. E. KaufmannThe GC6-74 consortiumNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q January Weiner Jeroen Maertzdorf Jayne S. Sutherland Fergal J. Duffy Ethan Thompson Sara Suliman Gayle McEwen Bonnie Thiel Shreemanta K. Parida Joanna Zyla Willem A. Hanekom Robert P. Mohney W. Henry Boom Harriet Mayanja-Kizza Rawleigh Howe Hazel M. Dockrell Tom H. M. Ottenhoff Thomas J. Scriba Daniel E. Zak Gerhard Walzl Stefan H. E. Kaufmann The GC6-74 consortium Metabolite changes in blood predict the onset of tuberculosis |
| description |
The tuberculosis pandemic requires new methods for diagnosing and containing infections prior to active disease. Here, the authors performed a multi-site observational study within sub-Saharan Africa and present serum and plasma metabolic signatures that can predict the onset of active TB with a high degree of sensitivity and specificity. |
| format |
article |
| author |
January Weiner Jeroen Maertzdorf Jayne S. Sutherland Fergal J. Duffy Ethan Thompson Sara Suliman Gayle McEwen Bonnie Thiel Shreemanta K. Parida Joanna Zyla Willem A. Hanekom Robert P. Mohney W. Henry Boom Harriet Mayanja-Kizza Rawleigh Howe Hazel M. Dockrell Tom H. M. Ottenhoff Thomas J. Scriba Daniel E. Zak Gerhard Walzl Stefan H. E. Kaufmann The GC6-74 consortium |
| author_facet |
January Weiner Jeroen Maertzdorf Jayne S. Sutherland Fergal J. Duffy Ethan Thompson Sara Suliman Gayle McEwen Bonnie Thiel Shreemanta K. Parida Joanna Zyla Willem A. Hanekom Robert P. Mohney W. Henry Boom Harriet Mayanja-Kizza Rawleigh Howe Hazel M. Dockrell Tom H. M. Ottenhoff Thomas J. Scriba Daniel E. Zak Gerhard Walzl Stefan H. E. Kaufmann The GC6-74 consortium |
| author_sort |
January Weiner |
| title |
Metabolite changes in blood predict the onset of tuberculosis |
| title_short |
Metabolite changes in blood predict the onset of tuberculosis |
| title_full |
Metabolite changes in blood predict the onset of tuberculosis |
| title_fullStr |
Metabolite changes in blood predict the onset of tuberculosis |
| title_full_unstemmed |
Metabolite changes in blood predict the onset of tuberculosis |
| title_sort |
metabolite changes in blood predict the onset of tuberculosis |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/05ed44b4c9294316afa2b3d18f1beb1a |
| work_keys_str_mv |
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| _version_ |
1718383257395920896 |