Dissecting Bacterial Cell Wall Entry and Signaling in Eukaryotic Cells: an Actin-Dependent Pathway Parallels Platelet-Activating Factor Receptor-Mediated Endocytosis

ABSTRACT The Gram-positive bacterial cell wall (CW) peptidoglycan-teichoic acid complex is released into the host environment during bacterial metabolism or death. It is a highly inflammatory Toll-like receptor 2 (TLR2) ligand, and previous in vivo studies have demonstrated its ability to recapitula...

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Bibliographic Details
Main Authors: Lip Nam Loh, Geli Gao, Elaine I. Tuomanen
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
Online Access:https://doaj.org/article/060763992dfb41f085dc1f6346b57cd1
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