ERAP1 Controls the Interaction of the Inhibitory Receptor KIR3DL1 With HLA-B51:01 by Affecting Natural Killer Cell Function
The endoplasmic reticulum aminopeptidase ERAP1 regulates innate and adaptive immune responses by trimming peptides for presentation by major histocompatibility complex (MHC) class I molecules. Previously, we have shown that genetic or pharmacological inhibition of ERAP1 on murine and human tumor cel...
Guardado en:
Autores principales: | Silvia D’Amico, Valerio D’Alicandro, Mirco Compagnone, Patrizia Tempora, Giusy Guida, Paolo Romania, Valeria Lucarini, Ombretta Melaiu, Michela Falco, Mattia Algeri, Daniela Pende, Loredana Cifaldi, Doriana Fruci |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/06850dcc2f5e4212b15a4f9dfffcba72 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Abundant CpG-sequences in human genomes inhibit KIR3DL2-expressing NK cells
por: Jason Pugh, et al.
Publicado: (2021) -
A Genome-Wide CRISPR/Cas9-Based Screen Identifies Heparan Sulfate Proteoglycans as Ligands of Killer-Cell Immunoglobulin-Like Receptors
por: Klara Klein, et al.
Publicado: (2021) -
PECULIARITIES OF NK CELLS DIFFERENTIATION: CD56dim AND CD56bright NK CELLS AT PREGNANCY AND IN NON-PREGNANT STATE
por: V. A. Mikhailova, et al.
Publicado: (2017) -
Phenotypic and functional changes of NK cells in patients with myelodysplastic syndrome and acute myeloid leukemia treated with hypomethylating drugs
por: D. I. Zhigarev, et al.
Publicado: (2021) -
EVALUATION OF MICROVESICLES FORMED BY NATURAL KILLER (NK) CELLS USING FLOW CYTOMETRY
por: V. A. Mikhailova, et al.
Publicado: (2018)