MCM2-7 complex is a novel druggable target for neuroendocrine prostate cancer

Abstract Neuroendocrine prostate cancer (NEPC) is a lethal subtype of prostate cancer that rarely develops de novo in primary tumors and is commonly acquired during the development of treatment resistance. NEPC is characterized by gain of neuroendocrine markers and loss of androgen receptor (AR), ma...

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Auteurs principaux: En-Chi Hsu, Michelle Shen, Merve Aslan, Shiqin Liu, Manoj Kumar, Fernando Garcia-Marques, Holly M. Nguyen, Rosalie Nolley, Sharon J. Pitteri, Eva Corey, James D. Brooks, Tanya Stoyanova
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/0691e54f4cb8403ba947ac009a53d0a8
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