Copper-catalyzed methylative difunctionalization of alkenes

While the trifluoromethylative difunctionalization of unactivated alkenes has been largely explored, methylative difunctionalization remains underinvestigated. Here, the authors report copper-catalyzed alkoxy- and azido-methylation reactions of alkenes leading to important synthetic building blocks...

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Autores principales: Xu Bao, Takayuki Yokoe, Tu M. Ha, Qian Wang, Jieping Zhu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/06a36734259d4f51981da412240aea26
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