Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain
Cyclic AMP and cGMP orchestrate a variety of cellular responses. Here, authors characterize the cGMP producing rhodopsin-guanylyl cyclase from C. anguillulae and derived adenylyl cyclase by a biochemical and structural approach which demonstrates the usability of these cyclases for optogenetic appli...
Enregistré dans:
Auteurs principaux: | Ulrike Scheib, Matthias Broser, Oana M. Constantin, Shang Yang, Shiqiang Gao, Shatanik Mukherjee, Katja Stehfest, Georg Nagel, Christine E. Gee, Peter Hegemann |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/06b7a3c5022e4c038a921dde8d876ca7 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
The inner mechanics of rhodopsin guanylyl cyclase during cGMP-formation revealed by real-time FTIR spectroscopy
par: Paul Fischer, et autres
Publié: (2021) -
Distribution of adenylyl cyclase/cAMP phosphodiesterase gene, CAPE, in streptophytes reproducing via motile sperm
par: Chiaki Yamamoto, et autres
Publié: (2021) -
The C-terminal region affects the activity of photoactivated adenylyl cyclase from Oscillatoria acuminata
par: Minako Hirano, et autres
Publié: (2019) -
Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase
par: Gemma Navarro, et autres
Publié: (2018) -
<i>Plasmodium falciparum</i>
Guanylyl Cyclase-Alpha and the Activity of Its Appended P4-ATPase Domain Are Essential for cGMP Synthesis and Blood-Stage Egress
par: Stephanie D. Nofal, et autres
Publié: (2021)